Having qualified from St George’s Hospital Medical School, University of London in 1987, Professor Shotliff undertook a General Medical Registrar rotation before studying for a Master Degree at the Hammersmith Hospital looking into the pathogenesis of diabetic retinopathy.

In June 1998 he was appointed Consultant Physician with an interest in Diabetes and Endocrinology at Kingston Hospital, Surrey where he ran a district general hospital diabetes and endocrinology service, with out-reach diabetes and endocrinology clinics and was Chairman of the Department of Medicine and Trust Information Technology Lead for his last 4 years there.

In March 2003 he moved to the Chelsea and Westminster Hospital and with 7 colleagues provides a busy in-patient and outpatient Endocrinology and Diabetes service. He has a particular interest in diabetes microvascular complications, new therapies, thyroid disease, PCOS and pituitary disease as well as running the adolescent diabetes, diabetic retinopathy clinics and a joint endocrine surgery clinic. He retired from the NHS in December 2024.

Professor Shotliff also held Honorary Consultant Endocrinologist Contracts with the Royal Brompton Hospital, and the Royal Marsden Hospital, London, and was an Honorary Senior Lecturer with Imperial College, Head of the Imperial Year 3 examination board, the Clinical Tutor for Chelsea and Westminster Hospital and ran an MSc module in Diabetic Retinopathy for the University of Roehampton Diabetes MSc program, and is still involved witha Cardiodiabetes MSc course with Plymouth University, where he was made an Associate Professor in the Department of Medicine at Plymouth University in 2019.